The recommended daily Garcinia Cambogia extract dosage is between 500 and 1500 milligrams (mg) per day (50% HCA), one hour before each meal. Most commercially available supplements contain 60% HCA. Hydroxycitric acid is believed to be the active ingredient in G. Cambogia. The plant is also known as Garcinia gummi-gutta. Dosages in clinical trials ranged from 1500 to 4,667 mg/day, which equates to between 25 and 78 mg per kilogram in body weight per day. The maximum recommended dose is 1500 mg per day.
The C. Gummi-gutta plant is a tropical species grown for its fruit. It is found in southeast Asia (Cambodia), Kerala in India and in western and central Africa. The fruit is about the size of a grapefruit and looks like a small, green pumpkin because it has number of lobes. The edible part of the plant is a spongy white substance. The G. Gummi-gutta trees are found in forests, as well is in plantations that would otherwise be given to coffee, spice and pepper production.
Similar in use to tamarind, it imparts a sour flavor to cooking in things like curries. There are some places where it is called Malabar tamarind. Its antibacterial properties make it useful for fish curing.
It was publicized in 2012 as being useful for losing weight. Since then, there has been an explosion of consumer interest in the product. One of its features that has made it so popular is that it has been shown to help people lose weight without needing to change their diet or lifestyle.
The plant has been suggested by veterinarians in Australia as a candidate for treating insulin resistance in the horse. Clinical trials conducted in 2004 in Omaha, Nebraska, on obese rats showed that 90 days of treatment with HCA resulted in a reduction in body weight with no changes in clinical chemistry, histopathology, hematology or any changes in major organs.
The chemical formula for HCA is C6H8O8. One particular form of HCA (2S, 3R)-HCA) inhibits specific enzymes in the intestines and pancreas. These are alpha-glucosidase and alpha-amylase, respectively. Alpha-glucosidase breaks down starches and disaccharides to glucose, whereas alpha-amylase breaks down larger carbohydrates, like starch and glycogen, to produce glucose and maltose.
According to Indian folk tradition, G. Gammi-gutta has been used for bowel and rheumatic complaints. It does have carminative properties, meaning it induces the expulsion of gas from the intestines or stomach. In southeast Asia, it is a popular food preservative and flavoring agent. The active ingredient in G. Gammi-gutta, HCA, has been reported to speed up metabolism and may enhance performance while exercising, although these effects remain to be confirmed.
Formal clinical trials are required to confirm what has been a largely anecdotal anti-obesity effect at the Garcinia Cambogia extract dosage. The foregoing has been prepared for information purposes only and should not be taken to be a recommendation or a substitute for professional medical advice. No one should ever embark on a weight loss program without first consulting their personal physician or other qualified medical professional who is familiar with their personal medical history.